Biodiversity and antimicrobial potential of bacterial endophytes from halophyte Salicornia brachiata

Extreme natural habitats like halophytes, marsh land, and marine environment are suitable arena for chemical ecology between plants microbes having environmental impact. Endophytes an ecofriendly option the promotion of plant growth to serve as sustainable resource novel bioactive products. The present study, focusing on biodiversity bacterial endophytes from Salicornia brachiata, led isolation around 336 endophytes. Phylogenetic analysis 63 revealed 13 genera with 27 different species, belonging 3 major groups: Firmicutes, Proteobacteria, Actinobacteria. 30% endophytic isolates various demonstrated broad-spectrum antibacterial antifungal activities against a panel human, plant, aquatic infectious agents. An isolate Bacillus amyloliquefaciens 5NPA-1, exhibited strong in-vitro activity human pathogen Staphylococcus aureus phytopathogen Xanthomonas campestris. Investigation through LC–MS/MS-based molecular networking bioactivity-guided purification identification three compounds lipopeptide class based 1H-, 13C-NMR MS analysis. To our knowledge, this is first report studying brachiata its endophyte. Overall, study provides insights into diversity associated extreme rich source metabolites remarkable agricultural applications therapeutic properties.